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But this pattern of cell death pathway was inconsistent with previous knowledge for there was no morphological alternation or DNA fragmentation
Saponin is a group of glycosides comprising one or more hydrophilic groups combined with lipophilic triterpenes or steroid derivatives
This adds to the difficulty in reconciling MS under a single pathophysiological umbrella, but also has implications for therapeutic design: this cytodegenerative component is not expected to respond to current anti-inflammatory disease-modifying drugs targeting acute/adaptive peripheral autoimmunity
Estrogen receptors are found in cardiomyocytes (heart muscle cells), neurons, airway cells, muscles, the uterus, testes, fat tissue, bone, breast, kidneys, and more
Redox Signal 7 , 919929 (2005)