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397 In addition, triple blockade of the aldosterone receptor, angiotensin-converting enzyme, and angiotensin receptors is also being evaluated

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American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

JYHL2021FMS13, JYHL2021MS30)

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Mechanistic investigations associate these outcomes with signaling pathways involving vascular endothelial growth factor receptor-2 (VEGFR-2) and downstream Akt-eNOS activation, processes that collectively facilitate efficient muscle tissue remodeling (5)