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Hypoglycemia is a real risk at doses above 60 mcg, particularly when combined with insulin or during caloric restriction

For example, people with pernicious anemia might need different doses because they cant make the right proteins

For clinically meaningful weight loss, GLP-1/GIP therapies have far stronger outcomes in major trials

For use as a supplemental source of B complex vitamins in cattle, swine and sheep

Even experienced doctors are sometimes stumped when interpreting high B12 blood values, so here is a little guide on how to proceed in such cases: Guide to High Vitamin B12 Blood Levels Sources E