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Infants born to mothers physically dependent on opioids will also be physically dependent and may exhibit respiratory difficulties and withdrawal signs [ see Use in Specific Populations (8.1)]

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Buprenorphine , a partial agonist available in formulations such as Suboxone (combined with naloxone), Sublocade, and Brixadi, presents a lower risk of overdose and has become a mainstay of outpatient care

[4] Neurofibromatosis type 1 (NF-1) is a risk factor for developing MPNSTs