A transdermal preparation is now being marketed
Studies have shown improved nerve conduction and symptom reduction with this active form
Clinical trials have demonstrated substantial glycemic control improvements and weight loss averaging 15-21% of body weight at higher doses
As with any injection, theres a small risk of soreness at the injection site, but serious side effects are extremely rare
Key characteristics: Short sequence length (16 amino acids), relatively straightforward to synthesise at high purity Frequently referenced in literature discussing mitochondrial-nuclear communication the concept that mitochondria may signal to the rest of the cell via peptides they encode Studied in metabolic research models exploring cellular energy regulation pathways AOD9604: A Modified Fragment of Human Growth Hormone AOD9604 is a synthetic peptide corresponding to a modified fragment of the C-terminus of human growth hormone (specifically, the region historically referred to as the GH fragment 176-191, with a modified terminus for stability)
Here in the UK, a B12 deficiency would usually mean 6 injections aver the course of a month (loading doses) then 1 every 3 months (maintenance doses)- a regime that seems dissatisfactory to the point of detriment to many many people, but one we have been stuck with for far too long