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The SIRT1/HIF2alpha axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy

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[DOI] [PubMed] [Google Scholar] 103.Bae J-E, Kim JB, Jo DS, Park NY, Kim YH, Lee HJ, et al

These studies indicate that STAT3 signaling can utilize NF-B components to evoke an immunosuppressive state in host tissues