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Studies 16 demonstrate that GLP-1 RAs enhance glycemic control and decrease hemoglobin A1C (HbA1c) levels by approximately 0.8-1.6%

Additionally, we performed quantitative amino acid profiling of individuals from konzo-prone regions which suggests a deficiency in cystine, the precursor for the antioxidant glutathione, which is required by GPx3 to effectively remove ROS from circulation 22

Collectively, these mechanisms illustrate how hypothyroidism predisposes the liver to steatosis and metabolic dysfunction

The nutritional approach is largely the same: adequate protein, gut and microbiome support, and a diet rich enough in micronutrients to support energy and long-term health

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Target: 68 mg weekly (standard)