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doi: 10.1007/978-3-030-27061-2_9 16 NakamuraMTNaraTY

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Preclinical research done in Toronto also showed that GLP-1 acted on the brain to reduce appetite, which helps with weight loss, and has been demonstrated to reduce the risk of heart attack and stroke

Tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs) carry different metabolic profiles but still require individualized assessment rather than blanket avoidance

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In its pivotal trial, 62% of patients treated with Saxenda lost at least 5% of their body weight compared with 34% of patients treated with placebo