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SILY when administered alone (at 280 mg/kg) reversed DEX-induced changes in body weight

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When administered into the brain circulation and cerebrospinal fluid of mice, DSIP showed a significant, dose-dependent reduction in pain response in the tail-pinch and hot-plate tests

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B 5, 4455 (2017).CrossRefGoogle Scholar Mondragn, L., Mas, N., Ferragud, V., de la Torre, C., Agostini, A., Martnez-Mez, R., Sancenn, F., Amors, P., Prez-Pay, E., and Orzez, M.: Enzyme-responsive intracellular-controlled release using silica mesoporous nanoparticles capped with -poly-L-lysine

In animal studies, Fang (42) et al