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More information about TUEs for medications to treat growth hormone deficiencies can be found on the USADA TUE page

J Biol Chem 279(44):4570845712 Nithya K, Angeline T, As P, Aj A (2019) Prevalence of Glutamate carboxypeptidase II C1561T, reduced folate carrier 1 A80G, and methionine synthase A2756G gene polymorphisms in patients with type 2 diabetes mellitus among South Indians

Broader gene expression and signaling effects have been summarized in experimental models

241 Mutations in the SIRT2 gene have also been reported in human cancers, impairing genome maintenance and promoting tumorigenesis

The medication is used for a wide range of indications

In addition, the enhancement of lysosomal function and lysosomal enzyme replacement can accelerate the clearance of accumulated pathogenesis-related proteins in neurodegenerative and cardiovascular diseases