Retraction in: Innov Pharm
Part of Clavicular's Looksmaxxing Stack GHK-Cu 50mg Glycyl-L-histidyl-L-lysine copper complex CAS: 49557-75-7 4,000+ Genes Modulated Pickart & Margolina 2018 Declines with age Natural Concentration Plasma levels fall ~60% from 20s to 60s Technical Data & References Chemistry, identifiers, and primary literature for GHK-Cu (Copper Tripeptide-1) available as blue lyophilized powder on Clav Tides
Phenomenal product
It is a short chain of three amino acids (alanine, histidine, and lysine) bound to a copper ion
Regulatory note: Both peptides are research chemicals, not FDA-approved (removed from 503A compounding Category 2 in Sept 2024
One possible interpretation of the available agonist-bound non-conducting KAR structures in pseudo four-fold and asymmetric LBD conformation is that they represent different steps of the desensitization process, which starts similar to AMPARs, with the rupture of D1-D1 interfaces in two intact LBD dimers, followed by dissociation of one LBD dimer and then the second (Zhou et al., 2025)