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Selenocysteine -lyase: biochemistry, regulation and physiological role of the selenocysteine decomposition enzyme

CagriSema vs Tirzepatide (REDEFINE 4): strong weight loss, but an important endpoint miss Novo Nordisk has announced headline results from the open-label phase 3 REDEFINE 4 trial comparing CagriSema (cagrilintide + semaglutide) vs tirzepatide 15 mg in obesity

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This dual action, increasing fat breakdown while blocking fat formation, creates a metabolic environment that favors net fat loss even when caloric intake is not dramatically reduced