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Calcitonin screening IS recommended in specific situations: when evaluating nodular thyroid disease (as part of the workup, not specifically because of tirzepatide), when a family history of MTC exists, and when MEN 2 is suspected

Current evidence does not show semaglutide causes birth defects, but manufacturers recommend stopping the medication at least two months before attempting conception since it wasn't extensively studied in pregnancy

Mild nausea and constipation typically fade within 1-2 weeks

Restoration of SIRT3 levels by SGLT2i is central to the regulation of antiglycolytic systems and activation of antioxidant and antifibrotic signaling cascades

A: Congratulations on your progress so far

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