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As its full safety profile remains under investigation, the following reflects current available data and known class effects: Gastrointestinal symptoms are the most common: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

Additionally, metal ion chelators, developed based on this hypothesis, need to overcome challenges such as adverse events and poor blood-brain barrier (BBB) permeability to demonstrate their potential therapeutic value

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Adv Nutr 2023;14:629-36.ArticlePubMedPMC 338