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It reduces appetite, slows gastric emptying, and supports insulin response

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Through attenuation of chronic hypothalamicpituitaryadrenal (HPA) axis overactivation, adaptogens such as Withania somnifera can normalize thyrotropin-releasing hormone (TRH) and thyroid-stimulating hormone (TSH) signaling, thereby improving peripheral thyroid hormone bioavailability (186)

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Some people find that skipping berberine on the day of their injection helps reduce the total burden on their digestive system