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2.18 Statistical analysis In this study, both cell and animal experiments were conducted using a blinded design

Furthermore, the interaction between the unliganded -CT and the FnIII-1 domain, together with the disulfide bonds between the two -CTs, restricts the conformational change of unliganded -CT, which is required for the binding of a second IGF1 molecule (Fig

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These included single dose applications of saline (1 ml i.p.), NaBPC157 (10 g/kg b.w.), L-NAME (NO antagonist / doses 50, 100, 150 mg/kg b.w.) and L-arginine (NO agonist / 100 mg/kg b.w

It contains an unusual gamma-glutamyl peptide bond

Evidence for the blend comes from studies on individual peptides