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Medications such as metformin [Glucophage], phentermine [Adipex-P], topiramate [Topamax], bupropion [Wellbutrin], and naltrexone [Revia] (sometimes used alone or in combination, [such as Contrave]) can be effective and are often available as inexpensive generics, sometimes for as little as $10 to $20 per month

From a health perspective, this degree of fat loss can translate into fewer heart attacks, fatty liver, and diabetes in the future

NHS access also varies by region

GLP-1 Analog Modulates Appetite, Taste Preference, Gut Hormones, and Regional Body Fat Stores in Adults with Obesity. Journal of Clinical Endocrinology & Metabolism, vol

Additionally, manufacturing pills at a massive scale might eventually help ease the supply shortages that have plagued popular injectable GLP-1s, though this is not yet guaranteed

Hypoglycaemia risk: Patients who are also taking insulin or sulfonylureas should be aware of an increased risk of hypoglycaemia