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However, titration with His, which forms 2: 1 complex in our experimental conditions and leads to fast demetallation of CuHSA, yielded K D equal to 34.7 4.5 fM (50 mM Hepes, 50 mM NaCl at pH 7.4)

(PubMed) Qawasmi A, Landeros-Weisenberger A, Bloch MH

As pU L 31 and pU L 34 are not components of mature extracellular virions, they were omitted from that analysis 21,45

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However, the drug does carry a boxed warning about thyroid cancer based on animal studies

Joseph JJ, Deedwania P, Acharya T, Aguilar D, Bhatt DL, Chyun DA, Di Palo KE, Golden SH, Sperling LS, American Heart Association Diabetes Committee of the Council on L