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Preclinical research suggests the compound enhanced neuronal survival and connectivity, and shows positive effects on oxidative stress, swelling, cell clean-up, blood-brain barrier integrity, and inflammation following brain injury, according to a corporate presentation

Published research in controlled laboratory models has examined selective GHRH receptor engagement, downstream somatotroph signaling, and IGF-1 axis modulation at the cellular level

Compounded GLP-1 medications are allowed in 45 states, excluding Mississippi, California, Louisiana, Iowa and Wisconsin.

One notable difference: semaglutide and tirzepatide have established prescribing information with FDA-approved dose ranges and flexibility for clinicians to hold patients at intermediate doses if tolerability is an issue

Research shows up to 40% of weight lost on GLP-1 medications is lean muscle, not fat