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The first was a diet-induced obese mouse study

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Recent studies have suggested that glycemic variability may serve as an independent risk factor for DN, affecting both peripheral and autonomic nerve functions (Zhang X

Who May Benefit from Dual-Action Therapy Versus GLP-1 Monotherapy Dual-agonist therapy may be appropriate for patients with type 2 diabetes, prediabetes, or obesity who have inadequate response to GLP-1 monotherapy or require more aggressive metabolic intervention

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That number could increase significantly over time as supply shortages of the drug are resolved, as indications for the drugs expand, and especially if health-insurance companies increase coverage for the drugs.