when did you start losing weight on tirzepatide vs. Semaglutide for Loss: What I Learned, What Worked, and What Didn't ~ What to Expect on Tirzepatide:

MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus

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If constipation becomes severe, adding fiber, magnesium, or a stool softener helps without interfering with semaglutide's effectiveness