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Modulation of kidney risk factors underlying renoprotective effects Several mechanisms have been proposed to explain how GLP-1 receptor agonists improve kidney function and outcomes (Figure 1)

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The active ingredient in Trulicity is dulaglutide, and for Ozempic, it is semaglutide

When researchers tested pure GLP-1 receptor agonists, including semaglutide , liraglutide, and exenatide, none of them increased the beating rate of isolated heart tissue