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Additionally, this approach activated the protein kinase R-like endoplasmic reticulum kinase (PERK)/active transcription factor 4 (ATF4) signaling pathway, crucial for endoplasmic reticulum stress regulation, and partially mitigated hepatic lipid accumulation

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Biochem Biophys Res Commun [Internet]

PMD are genetic disorders that directly impair OXPHOS proteins or its function by impacting the complex machinery involved in the OXPHOS process

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In this reviews literature, LBM measured by dual energy X-ray absorptiometry or bioelectrical impedance, while bioelectrical impedance analysis measures SMI