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Clinical manifestations can include acne, excessive body hair (caused by high androgen male hormone levels), irregular periods and infertility (due to infrequent or irregular ovulation), and metabolic issues, such as insulin resistance and metabolic syndrome, causing difficulties with weight management

These results suggest that membrane fluidity is important for the function of the membranous web

and a balanced Bacteroidetes-to-Firmicutes phylum ratio between 0.81.2, maintaining optimal energy metabolism (133, 134)

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