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CHO-K1 (ATCC #CCL-61) cells were maintained in F12 containing 10% (v/v) FBS, 100 units/mL penicillin and 100 mg/mL streptomycin at 37 C in 5% CO 2

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The sensitivity analysis excluding one trial with a short duration and one trial that recruited participants on background insulin therapy yielded similar results and reduced statistical heterogeneity

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