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431 participants were given either 3 g ALCAR daily for a year or a placebo daily for a year and were measured with two cognitive performance scales

Coinsurance for specialty tier drugs ranges from 25% to 33% in these plans, with 8 of the 12 national PDPs charging 25% and 2 charging 33%

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Importantly, this effect often attenuates over time with long-acting agents (tachyphylaxis), though the weight loss and glycemic benefits typically persist