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By activating several proteins involved in the TSS pathway and cystine uptake, including CBS, SLC7A11, GCLC, and GCLM, DMF increased GSH levels and produced a ferroptosis scavenging effect

PI cannot penetrate intact cell membranes and thus only stains cells whose membrane integrity is compromised, such as apoptotic or necrotic cells

Results are gradual and unpredictable

An oral formulation containing an inclusion complex of satraplatin and -cyclodextrin displayed increased bioavailability and antitumor effect

IL-13 enhances epithelial cell turnover and mucus production at the site of inflammation [1, 23]

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