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Interestingly, the observations extracted from computational analysis were in accordance with the calculated in vitro enzyme inhibition activities, i.e., stronger interaction of C3G (glycosylation of 3-OH group) via A-ring with binuclear copper ion results in its complete oxidation by the enzyme against EC and CH compounds

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Restoration of GLP-1 secretion by Berberine is associated with protection of colon enterocytes from mitochondrial overheating in diet-induced obese mice

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Compared with the rotenone group, the sulforaphane + rotenone group demonstrated increased protein expression of HO-1, 1.4-fold higher in the cerebral cortex and 1.6-fold higher in the striatum, respectively (Fig