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Pinch Your Skin and Insert the Needle at the Right Angle Using your thumb and forefinger, gently pinch a fold of skin at your chosen injection site to create a small pocket of tissue

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doi: 10.3390/ijms22084156 106 BentsaT

This will include a rectal examination with a gloved finger to detect tenderness, blockage, or blood in the rectum or colon

However, if the transdermal system has not been changed for more than 2 days (48 hours or more) in the middle of the cycle, a new dosage cycle should be started