dEmden MC, Shaw JE, Jones GR, Cheung NW
These results established semaglutide as a benchmark therapy in the weight loss medication landscape
Start your intake Who the program is built for Hims (Hims & Hers Health) is subscription telehealth aimed at adults seeking clinically supervised weight management without an in-person clinic
10.1016/j.bbamcr.2020.118890 145 LiuL.NiuY.GuoZ.WangC.LiuH.YangJ.et al (2025)
GLP-1 receptors are heavily expressed in the gastrointestinal tract, and GLP-1 receptor agonism appears to influence intestinal barrier function, gut motility, and potentially the gut microbiome composition
In clinical trials for weight management, tirzepatide produced average weight loss of 20-25% of body weight, roughly double what semaglutide achieves at comparable endpoints