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The reduction in renal function leads to fluid retention and further neurohormonal activation, combined with oxidative stress and anaemia, aggravating cardiac dysfunction

doi: 10.3389/fmolb.2025.1622186 Received 02 May 2025 Accepted 02 June 2025 Published 26 June 2025 Volume 12 - 2025 Edited by Roberta Marongiu, Cornell University, United States Reviewed by Larance Ronsard, Ragon Institute, United States Jorge Felipe Argenta Model, Federal University of Rio Grande do Sul, Brazil Updates Copyright 2025 Lizcano, Sanabria and Aviles

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