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However, it has been structurally modified to bind to albumin in the bloodstream, which dramatically extends its half-life to approximately six to eight days (with DAC formulation)

Over-the-counter pain relievers such as NSAIDs generally dont interact significantly with Wegovy, but should be used cautiously if you have other health conditions

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A Phase 2 clinical trial published in the New England Journal of Medicine (2023) demonstrated participants receiving retatrutide achieved up to 24.2% mean weight reduction over 48 weeks the highest reduction reported for any investigational compound in its class at that time