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If your vial has been exposed to temperatures above 30C (86F) for more than a few hours, discard it as a safety precaution

Furthermore, research by Sikiric et al

Vitamin B12 acne is included in a subset known as inflammatory acne. These include pustules (the white-capped, pus-filled ones), cysts and nodules (the hard, deep ones), and papules (similar to cysts, but not as large)

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Highly dosed with 3000 g vitamin B12

A Certificate of Analysis (COA) is included with each order, documenting the HPLC chromatogram, mass spectrometry data, and batch-specific test results