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Glutathione undergoes a reaction with the toxic substances, facilitated by enzymes such as glutathione S-transferases, to form a conjugate known as a glutathione adduct, which is then further metabolized in the liver to form mercapturic acid, a water-soluble compound that can be easily excreted through the urine
The amount of a given agent that will correspond to such an amount will vary depending upon factors such as the particular compound, disease condition and its severity, but is nevertheless routinely determined in a manner known in the art according to the particular circumstances surrounding the case, including, e.g., the specific agent being administered, the route of administration, the condition being treated, and the subject or host being treated
H., & Schellens, J
Water-soluble vitamins such as B1 and B12, that are not stored in the body, are at much higher percentage values, 183% and 250% respectively
References 1 AdessoS.MagnusT.CuzzocreaS.CampoloM.RissiekB.PacielloO.et al
Duntas, L
