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Data from clinical studies confirm user results

It works by enhancing insulin secretion, reducing glucagon levels, slowing digestion, and regulating appetite

The most common side effects are gastrointestinal: nausea, vomiting, diarrhea, constipation, and decreased appetite

It was demonstrated in animal studies that unabsorbed quaternary amines such as choline, phosphatidylcholine, betaine or l-carnitine can be metabolized by gut microorganisms to produce the intermediate compound trimethylamine (TMA)

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In my practice, I view it as a complementary, not competitive, ingredient: a reasonable addition for women who cannot tolerate retinoids, or as part of a layered approach for those who can