However, as weve explored, this discomfort is far from insurmountable
Four randomized controlled trials tested ALC in patients with neuropathy secondary to diabetes and to antiretroviral therapy for HIV
But I think in the hands of an experienced practice clinician that we will be able to control these adverse events. ACHIEVE-3 The ACHIEVE-3 trial included 1,698 adults with type 2 diabetes inadequately controlled with metformin, an HbA1c of 7% to 10.5% and a BMI of 25 kg/m 2 or more at baseline (mean age, 53.9 years
Research suggests it influences several overlapping biological systems simultaneously, which may explain why it shows up across such a wide range of tissue types in preclinical studies
Last reviewed: May 2026 Medically reviewed by Mohammed Lakhi Superintendent Pharmacist
Potential Biological effects of (-)-epigallocatechin-3-gallate on the treatment of nonalcoholic fatty liver disease