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High-Performance Liquid Chromatography (HPLC) provides the standard method for purity assessment, separating compounds to identify contaminants and verify peptide identity

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Protocol duration: Results from preclinical studies appeared over 28 to 42 day timeframes in mice

To test the hypothesis, we carried out a comprehensive analysis of proteomics and single-cell sequencing (scRNA-seq) in the young/aged mouse model of BLM-induced pulmonary fibrosis before and after the LNP-mRNA treatment

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10 L of isotonic saline containing 100 g/mL Nle-YI-(6) aminohexanoic amide as an internal standard is added to each sample on ice