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Because of unopposed estrogen, there's a relative estrogen dominance

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Some people seek glutathione therapy when experiencing: Persistent fatigue Brain fog High stress and burnout Frequent illness or slow recovery Glutathione therapy may also be part of a broader plan focused on long-term wellness and vitality

It doesnt negatively affect the bodys hormonal balance, but rather gives the endocrine system a boost to do what its naturally built to do, just better and more efficiently