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Acute toxicity studies in animals, if extrapolated to humans, implicate a single dose of 10-15 grams necessary to produce significant liver toxicity, although several human case reports have shown toxicity at doses less than 4 grams per day (likely due to having one or more risk factors for sensitivity to toxicity) (Amar 2007)

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In this study, the observed half-life of PF-06882961 was 4.3 to 6.1 hours

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Nach der Rekonstitution sollte die Loesung bei 2 bis 8 Grad Celsius gelagert und innerhalb von 28 Tagen verbraucht werden