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FIGURE 2 6 Conclusion and future perspectives Therapeutic approaches to address oxidative stress typically involve upregulating antioxidant signals such as NRF2, administering exogenous antioxidants, supplementing trace elements or nutrients, and implementing environmental interventions ( de novo GSH synthesis but also exhibits independent antioxidant effects

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Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gtzsche PC, Ioannidis JPA, et al