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These effects are largely mediated through activation of Wnt/-catenin, BMP2/Smad/Runx2, PI3K/Akt, MAPK, and GLP-1Rdependent cascades, supporting their potential as multifunctional modulators in regenerative medicine (Fig

1, Table 2 and Supplementary Section 5) seems more likely, while any effect on psychotic, mood and anxiety disorders appears less consistent and in need of further investigation

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Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

S., Helmby, H