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Secretion of pro-inflammatory cytokines (IL-6, IL-12, and TNF-) from macrophages was significantly inhibited by ARA-290

A reduction in liver fat content of at least 30% occurred in 5767% of survodutide-treated participants versus 14% on placebo, and improvement in fibrosis by at least one stage occurred in 3436% of survodutide arms versus 22% on placebo

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Lyophilized BPC-157 can be frozen at -20C for long-term storage