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Ann Nutr Metab 50(2):139146 Hoss GRW, Poloni S, Blom HJ, Schwartz IVD (2019) Three main causes of homocystinuria: CBS, cblC and MTHFR deficiency

[DOI] [PMC free article] [PubMed] [Google Scholar] (22).Wang Y, Zhang Z, Sun W, Tan Y, Liu Y, Zheng Y, Liu Q, Cai L, Sun J

It travels through the pelvis, past the piriformis muscle, and down the back of each thigh before branching into smaller nerves at the knee

Systemic administration (injectable or oral), which is less common than topical use and not part of approved or standard applications, would theoretically carry different safety considerations requiring appropriate clinical evaluation, though limited research on parenteral administration in animals has suggested acceptable safety profiles at moderate doses

Wang, S., Ma, X., Li, J., Lin, Y., & Liu, Y

All test solutions were prepared in 1 PBS (pH 7.4)