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Therapeutic Indications Skin brightening and pigmentation support Antioxidant supplementation Immunity and anti-aging support Adjunct in melasma and hyperpigmentation Recovery from oxidative-stress states Mechanism of Action L-Glutathione is the principal intracellular antioxidant, neutralising reactive oxygen species via its cysteine sulfhydryl group

some studies have suggested that it may worsen the drugs' efficacy

Patients with controlled hypertension or mild arrhythmia may still be candidates for treatment with appropriate monitoring

doi: 10.1016/j.diabres.2010.04.012, 23

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Vehicle was isotonic saline and compounds were administered at a volume of 1 l g 1