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Persistent headaches may indicate the need for dose adjustment, additional interventions, or investigation of alternative causes

Homocysteine is methylated to form the essential amino acid methionine in two pathways

Deterioration of the lung parenchyma (emphysema) and persistent inflammation and fibrosis of the small airways are hallmarks of COPD [7]

Two types of medications for ulcers and gastric reflux proton-pump inhibitors, such as omeprazole (Prilosec) and lansoprazole (Prevacid), and H2 blockers like cimetidine (Tagamet), famotidine (Pepcid), and ranitidine (Zantac) inhibit the release of stomach acid necessary to free dietary vitamin B12

Rev Cardiovasc Med 24(7):202

E., Mulla, C