Arsenite alters global histone H3 methylation
Helps maintain skin barrier integrity and hydration*
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The effectiveness of hydroxocobalamin was examined in a randomized, placebo-controlled, blinded study in cyanide-poisoned adult dogs assigned to treatment with vehicle (0.9% saline), or 75 or 150 mg/kg hydroxocobalamin
Vitamin B12 can interact with medications such as colchicine (a medicine used to treat gout), metformin (an anti-diabetic agent), excessive alcohol, vitamin C products, extended release potassium products, antibiotics such as gentamicin, neomycin, tobramycin, anti-seizure medications such as phenobarbital, phenytoin, primidone, medicines used to treat heartburn like H2 blockers such as cimetidine and proton pump inhibitors such as omeprazole, antacids such as ranitidine, cimetidine
It is extensively studied in preclinical models for its role in cellular protection, signaling pathways, and tissue-specific stress response research