Moreover, the weight loss achieved with GLP-1 RAs combined with lifestyle intervention approaches is comparable to that of surgical intervention, far surpassing the results adolescents can achieve through lifestyle changes alone ( This paper is a narrative review that references the SANRA guidelines for narrative reviews, but was not strictly written according to these guidelines

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Nrf2 interferes with the escape from cell death by interaction with other signaling pathways such as suppression of proapoptotic Jun Nterminal kinases (JNKs) (Elsby et al