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With respect to the requirement for Mg 2+ in ATP functions, essentially all of the ATP in the cell has Mg 2+ bound to the phosphates

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Rohloff, J

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Jacobs, et al

Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: a case-control study in an Indian population