Your doctor should assess several factors before approving discontinuation, including your current weight status and trajectory, the presence and control of obesity-related comorbidities (type 2 diabetes, hypertension, sleep apnea, cardiovascular disease), your readiness and capacity to implement intensive lifestyle modifications, available support systems and resources, and your history of weight cycling or previous weight loss attempts
doi: 10.1038/s41569-021-00569-6 96 MuQWangQYangYWeiGWangHLiaoJet al
Surgical management may be necessary in severe cases , including peritonitis, large abscesses, fistulae, or obstruction
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Those with a prior history of kidney stones have a higher baseline risk, and Wood says several other factors may increase vulnerability
For patients with type 2 diabetes or obesity, tirzepatide represents a well-studied, FDA-approved medication with demonstrated efficacy in clinical trials