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DPP-4 is responsible for the inactivation of GLP-1 by cleaving two N-terminal amino acids proline or alanine from natural peptides in the penultimate (P1) position

The Pendulum lineup at a glance AFU = Active Fluorescent Units, the live-cell count Pendulum reports via flow cytometry

GLP-1 medications complicate this

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doi: 10.1017/S0031182099004564 24 JemaM.FezaiM.BissingerR.LangF

While Ozempic is commonly used off-label for weight loss, these potential Wegovy alternatives are indicated for people with type 2 diabetes